Controlled Rate Freezers

Custom Biogenic Systems have come together with Mandel to offer the 2101 series Controlled Rate Freezing Systems. With a temperature range +50°C to -180°C and freezing rates of 0.01° to 99.9° per minute, these units are top of the line models.

These control rate freezers include the following features:

• Laptop controller using Windows-based operating system with unlimited programming capability
• Multi-colour graphing of sample, chamber and program temperature
• Temperature set points by sample or chamber
• Programs and freeze data saved to hard drive or disc
• Password-protected software
• Searchable database for freeze run history
• Freeze run graphs and data available via any standard USB printer
• 30 data fields available for each freeze run
• Continuous digital and graph display for time and temperature during operation
• Manual overrides for all operating functions
• Program temperature hold of 1 second to 99 hours
• Six pre-set easy to run freeze programs

High Capacity Rate Freezer

Improve outcomes by freezing larger quantities

• Reduce programming, freeze time and potential errors by freezing in fewer runs
• Decrease potential for accidents by reducing number of individual racks required
• Reduce sample exposure to ambient temperatures with quicker access to racks
• Use less LN2 than multiple batches in standard size freezer
• Save floorspace by using a single unit with smaller footprint than multiple standard size freezers
• Simplify monitoring of LN2 and power source by eliminating need for multiple freezers

Large Volume Freezing
Capacity to freeze thousands of samples in one run, saving you time and ensuring consistency in freeze runs

Precise Freeze Rates
Programmable temperature range of -180 to +50°C, with freeze rates of 0.01 to 99.9°C per minute

Multiple Fan and Probe Design
Ensures consistent temperature throughout the entire chamber space

Innovative Racking Systems
Choose how you want to freeze, retrieve, and move samples to long term storage or into clinical use

Fully Programmable Controller
Includes six pre-set run programs and the option to create your own freeze run programs using laptop or integrated touch screen

Reporting
Ability to chart samples by chamber and program temperature to ensure freeze run repeatability

IntelliRate™ i67C LN2 Controlled Rate Freezer

Perfectly sized to efficiently scale precision rate freezing as your needs grow

As cell-based research and bioproduction volumes increase, you need a repeatable freezing process that can efficiently improve post-thaw viability rates and cryopreservation quality at scale. We designed the new IntelliRate i67C to increase single-batch, liquid nitrogen (LN2) controlled rate freezing (CRF) capacities to meet your needs as development and manufacturing volumes increase.

Increase Rate Freezing Batch Capacity and Quality Cost Effectively
Expand controlled rate freezing throughput with significantly larger batches, without adding significant cost. With 40% more capacity than any other benchtop CRF, not only can the IntelliRate i67C increase production levels, but also ensure more process consistency and time savings by running thousands of samples in a single run.

Use Workspace and Staff More Efficiently
With its compact footprint accommodating larger capacity, the IntelliRate i67C frees up valuable workspace by using a single unit to freeze volumes, where normally multiple standard size freezers would be required. Fewer runs also simplify programming, setup, LN2 monitoring and power requirements.

Broaden Your Rate Programming Capabilities and Options
Use the largest touchscreen controller in its class to execute a wide range of preset and variable programming capabilities, including setup of repeatable, 21 CFR Part 11 compliant freeze profiles. With the IntelliRate i67C, a range of options are also available for enhanced multi-probe monitoring, racking and sample management.

More Freeze Capacity
67-litre (2.35 cu. ft.) volume inside the chamber delivers more batch capacity to freeze:

• 104 50mL bags
• 2166 2mL vials
• 100 cassettes
• 26 1-litre bags
• 272 canes

Flexible Power Requirements

• 120-volt, 50/60 Hz, 10 amp or
• 230-volt, 50/60 Hz, 10 amp

Programming and Control Features

• Six preset programs with unlimited variations
• Repeatable temperature rate changes within cycles
• Programmable temperature range of -180°C to +50°C
• Freeze rates of 0.01 to 99.9°C per minute
• 21 CRF Part 11 compliant reporting protocols

Options and Accessories

• Multi-probe version provides temperature monitoring at six additional customer-specified positions
• Innovative racking systems: choose how you want to freeze, retrieve and move samples to long-term storage or into clinical use
• Broad array of LN2 management, monitoring, sample handling and freezer accessories

Model 2101 Controlled Rate Freezer

• Laptop controller using Windows based operating system
• Unlimited programming capability
• Multi-colour graphing of sample, chamber and program temperature
• Temperature set points by sample or chamber
• Programs and freeze data saved to hard drive or disc
• Password protected software
• Searchable database for freeze run history
• Freeze run graphs and data available via any standard USB printer
• 30 data fields available for each freeze run
• Continuous digital and graph display for time and temperature during operation
• Manual overrides for all operating functions
• Temperature range +50°C to -180°C
• Freezing rates of 0.01° to 99.9° per minute
• Program temperature hold of 1 second to 99 hours
• Six pre-set easy to run freeze programs

Chamber Specifications

• Power requirements:
• 120 volt, 50/60 Hz, 10 amp, or
• 230 volt, 50/60 Hz, 10 amp
• Outside dimensions:
• Depth: 25 1/2” (648 mm) (including vent)
• Height: 29 1/4” (743 mm) (including computer)
• Width: 19 1/16” (484 mm) (including hose connection)
• Inside dimensions:
• Depth: 9 9/16” (243 mm)
• Height: 13 3/4” (349 mm)
• Width: 14” (356 mm)
• 28 litres