Verity Skid Process Scale Liquid Chromatography System

Verity Skid Process Scale Liquid Chromatography System

The VERITY® SKID is designed to automatically manage all purification steps involved in process scale chromatography such as generates elution mobile phase, injects sample, detects molecules, and collects fractions.

The unique design of this system allows to connect a large range and size of LC columns, such as HPLC, MPLC (High and Medium Pressure Liquid Chromatographic column), or CPC (Centrifugal Partition Chromatographic column) to optimize your production throughput, costs, and quality. Design in multiple configurations, the VERITY® SKID answers all the requirements of pharmaceutical molecule purification process.

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RELIABLE AND POWERFUL

  • Piston pump technology to achieve a large dynamic range of flowrate (from 1% to 100% of the pump capabilities)
  • Flow rate performance +/- 2% accuracy (with degassed water at 20°C) with repeatability better than 0.5% (In the same conditions)
  • Flowrate up to 300 L/h available in isocratic or binary high-pressure gradient
  • High precision automatic injection pump for optimized production time

EASY-TO-USE AND FLEXIBLE

  • Flexible configurations allowing to use columns from 30 to 300 mm ID
  • Conception made for easy cleanability of the frame and the structure
  • Mobile unit equipped with reinforced rotative wheels and directional brakes
  • Easy-to-use software allowing automated stack injections and a preset list of methods for automated production

SAFE AND COMPLIANT

  • Advance safety features with pressure transmitters, leak sensors and optional flowmeter
  • 21 CFR part 11 chromatographic software specifically designed for production
  • CE and Ex (Explosion Proof) certifications for use in a potentially explosive atmosphere
  • cGMP compliant

HPLC COLUMNS COMPATIBILITY

Select your SKID design according to your column ID. Large selection of columns thanks to the large dynamic range of flowrate from piston pump technology.

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MAIN CHARACTERISTICS

Select your Option design according to your process.

Flow Rates

SKID 30: 0.3 to 30l/h – (5 to 500ml/min)

SKID 60: 0.6 to 60 – (10 to 1000 ml/min.)

SKID 180: 1.8 to 180 – (30 to 3000 ml/min)

SKID 300: 3 to 300 – (50 to 5000 ml/min.)

Pressure

Up to 100 bars

Elution mode

Isocratique or Binary High-Pressure Gradient

Solvent inlet per pump

1 (up to 3 as option)

Injection mode

By injection pump or and automatic/manual injection loop

Detection

UV detector DAD 4 simultaneous wavelengths 200-400nm (200-600 nm, 200-800 nm as option)

Fractions collection

7 Fractions + 1 waste line (Other configurations as option)

Automatic pneumatic valves

4 ways Recycling valve (as option)

4 ways Backflush valve (as option)

4 ways Column bypass valve (as option)

2 x 3 ways Columns switching valves (as option)

Control

Software Controller Design for production and automation

CFR 21 Part 11 regulations compliant

Air supply

Pressure 6 to 8 bar

Electrical

Inlet power: mono 230 V~ or three-phase 380/400 V~; 50/60Hz based on configuration

Power consumption: 650 to 2500W based on configuration

Weight and dimensions

From 250 kg to 700 kg depending on the selected options

1600 mm H x 1200 mm W x 1650 mm D maximal dimension

Regulation

2006/42/EU Directives for machinery

2014/34/EU ATEX directives (as option)

Explosion proof

ATEX Zone II (as option)

Additional options

Filters

Heat Exchanger

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